Debi. NO question. Take the big camera. I carried mine all over England on my shoulder out of the bag and carried lens in the bag. Switching was no problem. Theft is also no problem if you are careful. Traveling does make people careless in a strange way...all the new things every day can disjoint your focus and you forget stuff. But just make it a priority. I am assuming taking photos IS a priority on your trip. Like weddings...when it's over all you have is your dress, your inlaws and your photos....except all you will have is your photos!! I haven't finished my book from last year of England yet but I am REALLY glad I have all those photos on my hard drive and backed up on my EHD!!
Re: Lens....I'd do what Mel said and just take the 75-300 you have along with your 50.
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just call me Uma
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