Laura beat me to it, with a much simpler answer! DPI is printing, it means dots per inch, so if you take a 300 ppi layout and print it on a 72 DPI dot matrix printer, it's still going to look cruddy.
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Sarah 
Equipment: Canon T2i (550D) with 18-55mm f/3.5-5.6, 55-250mm f/4-5.6, 50mm f/1.8, and 400mm f/5.6L lenses
Software: Windows 7, PSE 10 (Editor), PSE 6 (Organizer), and PSCS 4
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